Content Is Key
You must consider the long-term component in a web site. Sometimes they remain in place for a decade. Ask yourself - how disposable is your site?
Is your website what you truly wanted to make?
What I truly appreciate about responsive design is that content has moved to the forefront. People using phones and tablets want to view content. Designers need to make that content adaptable to all devices.
What I like most about the ideas that are coming forth is the return of content to the forefront. I have always said create some content and then add the design, without content you do not have anything worth visiting. With the rise of mobile devices and usage of these devices to access information, I think it is crucial to start making Web sites that can deliver usable content across all devices.